Alzheimer’s Disease is believed to be caused by abnormal buildup of protein in and around neurons. One of these proteins is called beta-amyloid, formed from a disulfide bond between two sulfur atoms.
The other protein is known as tau, formed from a disulfide bond between two sulfur atoms.
As with most proteins, both of these are made up of four building blocks, which when combined make up a molecule.
The individual amino acids are then put together in the correct sequence, forming a protein.
Alzheimer’s can only occur in specific combinations, which means that only a handful of proteins are responsible for a variety of symptoms in the majority of cases.
This makes it extremely difficult to identify early Alzheimer’s, since the progression of symptoms can depend on the stage that a patient is in.
What is Amyloid plaque
In Alzheimer’s patients, beta-amyloid accumulates in the brain, where it becomes lodged in specific areas.
The beta-amyloid protein produces a sticky substance known as a plaque, which clogs the blood vessels in the brain and slows down blood flow.
When this happens, neurons cannot receive the blood nutrients and oxygen necessary for normal brain function
which leads to the formation of amyloids, When Alzheimer’s develops, the affected brain has trouble making new connections,
and the neurons are unable to absorb the nutrients that are needed for them to grow and function properly.
proteins are no longer able to pass through the nerve cells and are unable to be transported to other parts of the body.
These are the areas that show the most degeneration as Alzheimer’s progresses.
They begin to form tangles and plaque, they eventually form into plaques, which start to grow larger.
These plaques continue to build up and harden, they will cause the formation of neurofibrillary tangles, which are another symptom of Alzheimer’s.
The tangles become progressively larger, the person suffering from Alzheimer’s gets less able to process information.
The person’s memory begins to diminish and the patient will begin to forget things that he or she may have previously learned.
How Alzheimer’s changes the brain
This is one of the most important questions of all. When someone has Alzheimer’s, the level of mental function is often affected, and the person may have difficulty performing simple tasks
such as remembering to do laundry or what a telephone number is for, and remembering their favorite vacation spot.
Because Alzheimer’s can progress so quickly, the person affected may begin to have problems speaking and even begin to forget personal details about their life.
If left untreated, the progression of Alzheimer’s will eventually lead to severe depression.
Another symptom of Alzheimer’s is a change in speech patterns.
While it is not always clear why some people will remember certain events with ease while others may be totally unaware of what is going on,
researchers believe that it may be because some people are better at recalling certain memories than others.
Another sign of Alzheimer’s is a lack of coordination. While there is no treatment for this type of condition,
many people have learned to coordinate the muscles in their hands and arms to make the simplest of movements like reaching for objects or writing.
Some people with Alzheimer’s may also begin to lose the ability to carry out their cognitive skills, and even recognize family members and friends.
The person may not know where they are, what time it is or how to cook a meal.
Many people who suffer from Alzheimer’s may be extremely irritable and not able to communicate.
Symptoms are often confused with depression and anxiety. Because they are still having memory issues,
patients with Alzheimer’s often worry that they are losing control of their life and may be losing their mental faculties.
They may even experience hallucinations and delusions.
When it comes to dealing with these symptoms, it’s best to remember that if you are experiencing these symptoms, it is not necessarily a sign of depression.
There are treatments for depression and anxiety that can help treat these symptoms, including counseling,
medication, psychotherapy, and lifestyle changes. It is very possible to live a full life as a result of dealing with these symptoms.